DNA typing of HLA-A, -C, -B, AND -DRB1 in the children with autism in the Republic of Macedonia

Bratislava Medical Journal Vol.116, No.1, p.14-19, 2015

Author: V. Trajkovski, M. Spiroski

Abstract

In the present study, we report the first DNA analysis of HLA class I and class II alleles in Macedonian autistic subjects. We have analyzed the HLA-A, -C, -B, DRB1 genotypes of 35 autistic patients, and 98 healthy unrelated Macedonians (control group). HLA DNA typing of class I genes was performed using a Reverse Line Strip method (RLS), and the Sequencing Based Typing method (SBT) was used for typing of class II genes. In the autistic subjects for HLA-A locus 14 alleles have been identified with 2 being predominant *02 (25.7 %), and *24 (18.6 %). Among the 11 identified HLA-C alleles, 3 were predominant such as *12 (20.0 %), *07 (17.1 %), and *03 (12.9 %). Among the 18 identified HLA-B alleles, 2 were predominant: *51 (18.6 %), and *18 (11.4 %). For HLA-DRB1 locus, 10 alleles have been identified with 2 of them predominant such as: *11 (21.4 %), and *01 (14.3 %).
The allele and haplotype frequencies in the patients group were compared to those of 98 control subjects. Our results showed significantly increased frequencies of HLA-C*03 (OR = 2.74*; χ2 = 4.68; p = 0.03), and HLA-DRB1*01 (OR = 3.10*; χ2 = 6.26; p = 0.012) alleles in autistic patients when compared to the controls.
The most frequent haplotype frequencies in autistic sample were A*11-C*12-B*52-DRB1*15 (2.9 %), A*24-C*03-B*55-DRB1*16 (2.9 %), and A*24-C*03-B*55-DRB1*16 (2.9 %), but they were not statistically significant when compared to the control group. None of our patients carried allele or haplotype, which were protective in our population.
Hardy-Weinberg equilibrium in autistic group showed that HLA-A (p < 0.03), HLA-C (p < 0.04), and HLA-DRB1 (p < 0.002) loci were in linkage disequilibria.
In the control group, we found only for the HLA-DRB1 locus linkage disequilibrium (p < 0.002).
Our results demonstrated the association of HLA-C*03 and HLA-DRB1*01 alleles with Macedonian autistic patients (Tab. 7, Ref. 37).

Keywords: HLA-DNA typing, autism, allele frequencies, haplotype frequencies, Republic of Macedonia.

doi:10.4149/BLL_2015_003

Source: http://www.elis.sk

Plasma concentration of immunoglobulin classes and subclasses in children with autism in the Republic of Macedonia: retrospective study

Croat Med J. 2004 Dec;45(6):746-9.
Trajkovski V1, Ajdinski L, Spiroski M.

Abstract

AIM:

To examine plasma concentration of IgA, IgM, IgG classes, and IgG1, IgG2, IgG3, and IgG4 subclasses in children with autism.

METHODS:

Infantile autism was diagnosed by the Diagnostic and Statistical Manual for Mental Disorders (DSM)-IV and the International Classification of Diseases (ICD)-10 criteria. Plasma samples were collected from 35 autistic subjects, and their 21 siblings (biological brothers and sisters) who served as healthy controls. Plasma samples were separated by centrifugation and stored at -20 degrees C until the determination. Plasma immunoglobulin classes (IgM, IgA, IgG) and subclasses (IgG1, IgG2, IgG3, IgG4) were determined using a nephelometer.

RESULTS:

Plasma concentrations (mean+/-standard deviation) of IgM and IgG in autistic children (1.36+/-0.31 g/L and 13.14+/-1.27 g/L, respectively) were significantly higher (p=0.031 and p=0.023, respectively) in comparison with their healthy brothers or sisters (1.20+/-0.15 g/L and 12.39+/-0.96 g/L, respectively). Children with autism had significantly higher plasma concentrations of IgG4 (p<0.001) compared to their siblings (healthy brothers or sisters). Plasma concentration of IgA, IgG1, IgG2, and IgG3 were similar in autistic children and their healthy brothers or sisters. Increased plasma concentration of IgG1 was found (p=0.027) in autistic males (8.06+/-2.40), as compared with their healthy brothers (5.24+/-4.13 g/L). Plasma concentrations of IgG (14.28+/-3.66 g/L), and IgG1 (9.41+/-2.20 g/L) in autistic females were increased (p=0.012 and p=0.021, respectively) in comparison with IgG (11.07+/-2.07) and IgG1 (6.37+/-3.38 g/L) in their healthy sisters.

CONCLUSION:

Children with autism have increased plasma concentration of immunoglobulines. Increased immunoglobulines in children with autism could be a result of impaired development of the immune system, and/or genetic factors connected with defense mechanism in these children.

PMID: 15578810

Source: https://www.ncbi.nlm.nih.gov/pubmed/

MEDICAL GENETICS AND ETHICS

Vladimir TRAJKOVSKI

Abstract

Fast development of medical genetics and it’s subdisciplines is noticed in last thirty years. Modern diagnostic methods made possible to establish human genom and its impairment. In human genetics, ethic is main principle in working. Ethic is science about biggest goodness for human or society, and its aim pro­tecting human health.

Today's conditions for leaving and science development open a wide way for ethical approaches, but also for non-ethical manipulations with human even before his conception. We must keep to attitude that without law, with our behavior will must conduct our conscience. It is best to have neutral eugenetic attitude, which allows free ethical choice of each individual, in any case, for the well being of man.

Source: http://jser.fzf.ukim.edu.mk/index.php/journal-archive/252-1999/1999-1-2-articles/2264-2009-08-15-20-51-02

Список на семинарски теми по предметот МОИ - 2018

Почитувани студенти,

Во прилог е списокот на семинартски теми по предметот Медицински основи на инвалидноста. Пријавени се точно 50 студенти што не е лош број. Крајниот рок за предавање во печатена и електронска форма е 15 април 2018 година. Среќно подготвување на истите.

Број на индекс	Тема на семинарска работа
24535/17	Аудиометрија
24538/17	Развојни аномалии на ‘рбетникот и ‘рбетниот мозок
24585/17	Класификација на ментална ретардација
10102/17	Епидемиологија на ментална ретардација
24513/17	Етиологија на ментална ретардација
24515/17	Глауком
24510/17	Хидроцефалус
24572/17	Генетика на ментална ретардација
10113/17	Myasthenia gravis
24553/17	Методи на испитување на слухот
24206/17	Хиперкинетски синдром
24509/17	Мултипна склероза
24547/17	Третман на ментална ретардација
10110/17	Превенција на ментална ретардација
10107/17	Шизофренија
24527/17	Menkes-ова болест
24577/17	Ретов синдром
9998/17	Нарушувања на говорот
10074/17	Акутни воспаленија на средното уво
10062/17	Хронични воспаленија на средното уво
10084/17	Мениерова болест
10027/17	Отосклероза
24571/17	Отогени компликации
8555/14	Нарушувања на фонацијата
24508/17	Офталмолошки тестови
10112/17	Кратковидост
10046/17	Далекувидост
24523/17	Астигматизам
10080/17	Страбизам
10009/17	Развојни аномалии на мозокот и черепот
10032/17	Катаракта
24549/17	Церебрална парализа
24516/17	Кохлеарен имплант
10024/17	Холестеатом
10075/17	Miler-Dicker синдром
24529/17	Rubinstein Taybi синдром
10039/17	Функционална амблиопија
24539/17	Наглувост и глувост
10092/17	Smith-Magenis синдром
24522/17	Фенилкетонурија
24543/17	Галактоземија
24208/17	Charcot-Marie-Tooth болест
24574/17	Неврофиброматоза
10111/17	Туберозна склероза
24506/17	Афазија
10028/17	Нистагмус
10051/17	Tay-Sachs- ова болест
10042/17	Аутизам
10058/17	Krabbe-ова болест
10090/17	Neimann-Pick- ова болест

Предметен наставник

EXPLORATORY STUDY: STRESS, COPING AND SUPPORT AMONG PARENTS OF CHILDREN WITH AUTISM SPECTRUM DISORDERS

Meri NOLCHEVA1
Vladimir TRAJKOVSKI2

1Unemploded special educator, Skopje, Macedonia
2University “Ss. Cyril and Methodius”, Faculty of Philosophy, Institute of Special Education and Rehabilitation, Skopje, Macedonia

Abstract

Introduction:Each year more families are confronted with unique challenges related to raising a child with ASD. Parenting stress is a significant aspect of fulfilling the role as a parent, and having a child with ASD greatly influences the experienced stress. The literature review indicates that parenting stress is inversely proportional to family support and coping mechanisms.

Aim:Appraising the stress level among parents of children with ASD, the coping mechanisms and the level of family support, in comparison with parents of children diagnosed with ID.

Method:A group of parents of children with ASD (N=35) and a second group of children with ID (N=35) completed four questionnnaires: PSI-SF, Brief COPE, FSS and demographic questionnaire. The data was analyzed using t-test for comparison, Chi-square test for comparing frequency distributions and Pearson coefficient for correlation, with p<r;0.05 level of significance

Results:Parenting stress did not differ between the two groups. The coping mechanisms used by the parents of children with ASD showed that increased usage of distraction (r=0.469) and disengagement (r=0.567) increased the level of parenting stress. Family support (r=-0.415) is a key buffer and coping mechanism for managing the stress in parents of children with ASD.

Conclusion:There are no differences in the level of stress, coping mechanisms and the level of support comparing parents of children with ASD and ID.

Keywords: autism spectrum disorder, intellectual disability, parenting stress, coping mechanisms, family support

Citation: Nolcheva M, Trajkovski V. Exploratory study: stress, coping and support among parents of children with autism spectrum disorders. J Spec Educ Rehab 2015; 16(3-4):84-100. DOI: 10.1515/JSER-2015-0013

Macedonia and Autism

Vladimir Trajkovski

First Online: 27 July 2017
DOI: https://doi.org/10.1007/978-1-4614-6435-8_102172-1

Historical Background

The Republic of Macedonia has gone through a long and painful process of transition during last 25 years. The cumulative effect of the transitional recession and the socially stressful process of transition have most seriously affected marginalized groups, such as persons with autism spectrum disorders being among the most vulnerable (Trajkovski 2008).

Autism in Macedonia has a short history. It is not like the history of autism in the USA or other western developed countries. For many decades, especially during the communist period of Yugoslavia, children with autism were diagnosed as mentally retarded, schizophrenic, or some other diagnosis. Children and adults with autism missed regular treatment because of inadequate institutions, lack of finances, parental ignorance, and prejudices in the society. Many of the children with autism have been placed into big institutions such as the Special Institute in Demir Kapija. Because of the poor economic situation, low...

How to cite
Trajkovski V. (2017) Macedonia and Autism. In: Volkmar F. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY

Publisher NameSpringer, New York, NY
Online ISBN978-1-4614-6435-8

Source: https://link.springer.com

HOW TO SELECT APPROPRIATE STATISTICAL TEST IN SCIENTIFIC ARTICLES

Vladimir TRAJKOVSKI

Journal of Special Education and Rehabilitation
Institute of Special Education and Rehabilitation,
Faculty of Philosophy,
University Ss. Cyril and Methodius
Skopje, Macedonia

Abstract

Statistics is mathematical science dealing with the collection, analysis, interpretation, and presentation of masses of numerical data in order to draw relevant conclusions. Statistics is a form of mathematical analysis that uses quantified models, representations and synopses for a given set of experimental data or real-life studies. The students and young researchers in biomedical sciences and in special education and rehabilitation often declare that they have chosen to enroll that study program because they have lack of knowledge or interest in mathematics. This is a sad statement, but there is much truth in it.

The aim of this editorial is to help young researchers to select statistics or statistical techniques and statistical software appropriate for the purposes and conditions of a particular analysis. The most important statistical tests are reviewed in the article.

Knowing how to choose right statistical test is an important asset and decision in the research data processing and in the writing of scientific papers. Young researchers and authors should know how to choose and how to use statistical methods. The competent researcher will need knowledge in statistical procedures. That might include an introductory statistics course, and it most certainly includes using a good statistics textbook. For this purpose, there is need to return of Statistics mandatory subject in the curriculum of the Institute of Special Education and Rehabilitation at Faculty of Philosophy in Skopje. Young researchers have a need of additional courses in statistics. They need to train themselves to use statistical software on appropriate way.

Keywords: statistical test selection, statistics, scientific article, statistical software

Citation: Trajkovski V. How to select appropriate statistical test in scientific articles. J Spec Educ Rehab 2016; 17(3-4):5-28. doi: 10.19057/jser.2016.7

20 YEARS JOURNAL OF SPECIAL EDUCATION AND REHABILITATION - A PERIOD OF CONTINUOUS DEVELOPMENT

Vladimir TRAJKOVSKI1
Doncho DONEV2

1Journal of Special Education and Rehabilitation
Institute of Special Education and Rehabilitation,
Faculty of Philosophy,
University Ss. Cyril and Methodius
2Institute for Social Medicine, Faculty of Medicine,
University „Ss. Cyril and Methodius“,
Skopje, Republic of Macedonia

Abstract

Introduction and goal: The first edition of the “Journal of Special Education and Rehabilitation” was released for the first time in 1997, and over the past 20 years, 37 issues have been published. In the Journal different kinds of articles are published from several scientific disciplines such as special education and rehabilitation, medicine, pedagogy, psychology, social politics, law and others. The goal of this editorial is to review the 20 years’ existence of the “Journal of Special Education and Rehabilitation” and to point out the future activities for the promotion of the quality of published articles and the integrity and visibility of the journal.

Methods: Review and analysis of the documentation of the journal as well as the evidence of submitted, rejected and accepted manuscripts, the structure of published articles by according to their uniqueness, and other specific moments in the development of the journal from its founding in 1997 – and especially the achievements in the period from 2008 to 2016.

Results: Over the past nine years we have noticed a growth in the number of authors and co-authors from the published articles by 358, from 28 different countries. The rate of acceptance of new articles has reduced from the original 93% in the first years of the foundation of the journal to 33% in the last three years. The majority of published articles come from authors from Macedonia which we can find in 31 articles or 27.7% from the overall published articles. The majority of authors have published original manuscripts (n= 87 or 53%), and then we have 12% articles of revision and 11.5% scientific articles. With regard to the different sections of the journal, the most published are news and information that are not subject to review (28%) while from the articles that are reviewed the most represented section is from special education and rehabilitation with a total of 16.5% from the overall number of published articles.

Conclusion: The “Journal of Special Education and Rehabilitation” is a journal that undertakes review on its articles and has an open access policy, which marks a continuous progress in quality and visibility with an appointed goal to serve as a solid medium to enhance scientific research and to promote professional achievements in the field of special education and rehabilitation and the similar fields in biomedicine in the Republic of Macedonia and abroad.

Keywords: Journal of Special Education and Rehabilitation, 20 years, reviewed journal, open access, publishing ethics and integrity

Citation: Trajkovski V, Donev D. 20 years Journal of Special Education and Rehabilitation - a period of continuous development. J Spec Educ Rehab 2017; 18(1-2):5-16. 

DOI: 10.19057/jser.2017.15

Ophthalmic manifestations in children and young adults with Down syndrome and congenital heart defects

Ljubic A, Trajkovski V, Tesic M, Tojtovska B, Stankovic B.

Abstract

PURPOSE:

To investigate whether different types of ocular manifestations are associated with congenital heart disease (CHD) in a large Caucasian population of children and young adults with Down syndrome (DS).

METHODS:

Population-based, case-control study which included 185 subjects with DS (mean age 13.2 ± 7.9 years), who reported presence or absence of CHD; DS with CHD group (51 subjects, mean age 10.6 ± 5.6 years) and DS without CHD (134 subjects, mean age 14.2 ± 8.4 years).

RESULTS:

In our sample with DS and CHD, strabismus was found in 15 subjects (29.4%), nystagmus in 1 (2.0%), epiblepharon in 21 (41.2%) and Brushfield spots in 15 (31.3%). In the DS without CHD group, strabismus was found in 38 participants (28.4%), nystagmus in 13 (9.7%), epiblepharon in 31 (23.5%) and Brushfield spots in 21 (16.0%). Only the variables epiblepharon and presence of Brushfield spots differed significantly between the two groups (p = 0.02 and p = 0.03, respectively). Hyperopia was present in 26 participants (53.1%) in the DS with CHD group, and in 65 (57.0%) in the DS without CHD group. Oblique astigmatism was present in 25 (52.1%) in the DS with CHD group and in 61 (53.5%) in the DS without CHD group.

CONCLUSIONS:

Frequencies of DS participants presenting with strabismus, nystagmus, hyperopia and oblique astigmatism were not statistically different between those with CHD and those without CHD in this sample. Further studies are needed to confirm if there are associations between the presence of Brushfield spots or epiblepharon and CHD in patients with DS.

KEYWORDS: Brushfield spots; Down syndrome; congenital heart defects; epiblepharon; nystagmus; refractive errors; strabismus

PMID: 25777312 

DOI: 10.3109/09286586.2015.1017652

Source: https://www.ncbi.nlm.nih.gov 

Parent education in autism spectrum disorder - a review of the literature

David Preece orcid.org/0000-0002-3182-1640 ; Centre for Education and Research, University of Northampton, United Kingdom
Vladimir Trajkovski orcid.org/0000-0002-8369-9501 ; University of SS Cyril and Mehodius, Skopje, Republic of Macedonia

Abstract
Families living with autism spectrum disorder (ASD) face many challenges, affecting not only the child with ASD and development but also family functioning and quality of life. Parent education (PE) in ASD has been identified as a priority intervention for this group both internationally and nationally. However, though there is a large body of literature regarding parent training (PT) in specific therapeutic approaches, a narrative literature review of databases found only 12 papers reporting on research into PE. Overall, PE is shown to be a positive intervention which can lead to reductions in stress and anxiety, improved coping, improved parent-child interaction and communication, improved understanding of ASD, efficacy and confidence and improved parental quality of life. Four key themes – impact, delivery, content and local/cultural issues – are discussed, weaknesses and problems within the literature are acknowledged, and the need is identified for further research into such interventions.

Key words
Autism spectrum disorder; parents; parent education

Hrčak ID: 183851
UDK: 364: 616.895
URL: https://hrcak.srce.hr/183851

A Pilot Study of a Behavioral Parent Training in the Republic of Macedonia

Hansen BD, Orton EL, Adams C, Knecht L, Rindlisbaker S, Jurtoski F, Trajkovski V.

Abstract

Parenting children with autism in countries with limited professional and financial resources can be overwhelming. Parent training led by non-governmental organizations may help alleviate some of these burdens. The present pilot study was conducted in the Republic of Macedonia, a country located in Southeastern Europe. The purpose of the study was to evaluate a parent training model for disseminating evidence-based practices through didactic and pyramidal training strategies. Results indicated that children improved on a number of different behaviors and results provide some evidence that parenting confidence and distress improved.

KEYWORDS: Behavior analysis; Behavioral parent training; International settings
PMID: 28374208 

DOI: 10.1007/s10803-017-3112-6

Source: https://www.ncbi.nlm.nih.gov/

Association of Prenatal Ultrasonography and Autism Spectrum Disorder

N. Paul Rosman, MD1,2,3,4; Rachel Vassar, MD5,6; Gheorghe Doros, PhD7; et alJames DeRosa, MPH8;Allison Froman, MPH8;Audrey DiMauro, MD, PhD5,9;Sherry Santiago, MD3,10;Jodi Abbott, MD11
JAMA Pediatr. Published online February 12, 2018. doi:10.1001/jamapediatrics.2017.5634

Abstract

Importance The prevalence of autism spectrum disorder (ASD) has been increasing rapidly, with current estimates of 1 in 68 children affected. Simultaneously, use of prenatal ultrasonography has increased substantially, with limited investigation into its safety and effects on brain development. Animal studies have demonstrated that prenatal ultrasonography can adversely affect neuronal migration.

Objective To quantify prenatal ultrasound exposure by the frequency, timing, duration, and strength of ultrasonographic scans in children with later ASD, developmental delay, and typical development.

Design, Setting, and Participants This case-control study included 107 patients with ASD, 104 control individuals with developmental delay, and 209 controls with typical development. Participants were identified from medical records based on prenatal care and delivery at Boston Medical Center, a diverse, academic, safety-net medical center, from July 1, 2006, through December 31, 2014, with a gestational age at birth of at least 37 weeks. Data were analyzed from May 1, 2015, through November 30, 2017.

Exposures Ultrasonographic exposure was quantified by the number and timing of scans, duration of exposure, mean strength (depth, frame rate, mechanical index, and thermal index), and time of Doppler and 3- and 4-dimensional imaging.

Main Outcomes and Measures Among participants with ASD and controls with developmental delay and typical development, ultrasound exposure was quantified and compared per trimester and for the entire pregnancy, with adjustment for infant sex, gestational age at birth, and maternal age.

Results A total of 420 participants were included in the study (328 boys [78.1%] and 92 girls [21.9%]; mean age as of January 1, 2016, 6.6 years; 95% CI, 6.5-6.8 years). The ASD group received a mean of 5.9 scans (95% CI, 5.2-6.6), which was not significantly different from the 6.1 scans (95% CI, 5.4-6.8) in the developmental delay group or the 6.3 scans (95% CI, 5.8-6.8) in the typical development group. Compared with the typical development group, the ASD group had shorter duration of ultrasound exposure during the first (290.4 seconds [95% CI, 212.8-368.0 seconds] vs 406.4 seconds [95% CI, 349.5-463.3 seconds]) and second (1687.6 seconds [95% CI, 1493.8-1881.4 seconds] vs 2011.0 seconds [95% CI, 1868.9-2153.1 seconds]) trimesters but no difference in the number of scans. The ASD group had greater mean depth of ultrasonographic penetration than the developmental delay group in the first trimester (12.5 cm [95% CI, 12.0-13.0 cm] vs 11.6 cm [95% CI, 11.1-12.1 cm]). The ASD group had greater mean depth than the typical development group during the first (12.5 cm [95% CI, 12.0-13.0 cm] vs 11.6 cm [95% CI, 11.3-12.0 cm]) and the second (12.9 cm [95% CI, 12.6-13.3 cm] vs 12.5 cm [95% CI, 12.2-12.7 cm]) trimesters.

Conclusions and Relevance This study found significantly greater mean depth of ultrasonographic penetration in the ASD group compared with the developmental delay group in the first trimester and compared with the typical development group in the first and second trimesters. Further research is needed to determine whether other variables of ultrasound exposure also have adverse effects on the developing fetus.

Source: https://jamanetwork.com

Warburg effect hypothesis in autism spectrum disorders

Warburg effect hypothesis in autism Spectrum disorders.

Vallée A, Vallée JN.

Mol Brain. 2018 Jan 4;11(1):1. 

Autism spectrum disorder (ASD) is a neurodevelopmental disease which is characterized by a deficit in social interactions and communication with repetitive and restrictive behavior. In altered cells, metabolic enzymes are modified by the dysregulation of the canonical WNT/β-catenin pathway. In ASD, the canonical WNT/β-catenin pathway is upregulated. We focus this review on the hypothesis of Warburg effect stimulated by the overexpression of the canonical WNT/β-catenin pathway in ASD. Upregulation of WNT/β-catenin pathway induces aerobic glycolysis, named Warburg effect, through activation of glucose transporter (Glut), pyruvate kinase M2 (PKM2), pyruvate dehydrogenase kinase 1(PDK1), monocarboxylate lactate transporter 1 (MCT-1), lactate dehydrogenase kinase-A (LDH-A) and inactivation of pyruvate dehydrogenase complex (PDH). The aerobic glycolysis consists to a supply of a large part of glucose into lactate regardless of oxygen. Aerobic glycolysis is less efficient in terms of ATP production than oxidative phosphorylation because of the shunt of the TCA cycle. Dysregulation of energetic metabolism might promote cell deregulation and progression of ASD. Warburg effect regulation could be an attractive target for developing therapeutic interventions in ASD.

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/29301575/

#ESIPP обука за родители на деца со аутизам во Дебар

Почитувани родители,

Ве покануваме на седмата обука за родители во рамките на #ESIPP проектот. Обуката ќе се одржи во периодот од 17 до 18 февруари 2018 воООУ „Саит Најдени” во општина Дебар.

Ве молиме да го потврдите вашето присуство кај господинот Беким Аме или на e-mail qendraepersonavemeaftesitekufizuar_poraka@hotmail.com или president@mssa.org.mk најдоцна до 14.02.2018 година.

Обуките се бесплатни и се наменети за исклучително само за родители (или членови на семејствата) на деца, адолесценти и возрасни лица со аутизам. За жал, обуките не се наменети за стручни лица и професионалци. Бројот на родители е ограничен на 20.

АГЕНДА

Сабота (17.02.2018)
Место: ООУ „Саит Најдени”

11:00- 12:30 Проф. д-р Владимир Трајковски (МНЗА) Вовед во аутистичниот спектар на нарушување

12:30-12:45 Пауза за кафе

12:45-14:15 Ана Шикалеска (МНЗА) Значењето на визуелната структура и нејзина имплементација

14:15-14:30 Пауза за кафе

14:30-16:00 Д-р Јасмина Трошанска (МНЗА) Справување со сензорната чувствителност

16:00-16:30 Дискусија


Недела (18.02.2018)
Место: ООУ „Саит Најдени”

09:00- 10:30 Д-р Јасмина Трошанска (МНЗА) Комуникацијата и нејзиното влијание врз однесувањето

10:30-10:45 Пауза за кафе

10:45-12:15 Ана Шикалеска (МНЗА) Позитивни пристапи кон социјалниот развој и интеракција

12:15-12:30 Пауза за кафе

12:30-14:00 Д-р Јасмина Трошанска (МНЗА) Разбирање и справување со предизвикувачкото однесување

14:00-14:30 Дискусија

Тренери:
Проф. д-р Владимир Трајковски
Д-р Јасмина Трошанска
Ана Шикалеска

Обуките се бесплатни и се организираат во рамките на проектот „Еднаквост и социјална инклузија преку позитивно родителство (Equity and Social Inclusion trough Positive Parenting – ESIPP) Проектот е со број: 2015-1-UK01-KA204-013397 и е дел од Еразмус + програмата на Националната агенција за европски образовни програми на Англија, Клучна акција: Соработка заради иновации и размена на добра пракса и Тип на акција: Стратешко партнерство за едукација на возрасни. Координатор на проектот е Универзитетот Нортхемптон, а додека пак партнерски организации се: Едукациско-рехабилитацискиот факултет од Загреб, Центар за аутизам од Загреб, Аутизам Европа со седиште во Белгија, Центар за развој и поддршка на деца и адолесценти со аутистичен спектар на нарушувања од Кипар, Европски универзитет од Кипар, Македонско научно здружение за аутизам од Македонија, Таргет аутизам и Аутизам Консерн од Англија. 

Целите на проектот се:

• Создавање на модел заснован на научни докази за едукација на родители на деца со аутизам кој ќе може да се користи во Европа.
• Создавање на програма и еколошки материјали за обука на родители.
• Употреба на материјалите во едукација на семејства на деца со аутизам во региони каде што претходно не биле спроведувани едукации.
• Оценка на употребата на материјалите и влијанието на обуката преку квалитативни и квантитативни анализи на податоци.
• Споделување на моделот на програма за едукација на родители, алатките и материјалите со засегнатите страни и давање на препораки на креаторите на политики и оние кои донесуваат одлуки.

Повеќе за проектот можете да прочитате на www.esipp.eu

Претседател на МНЗА

СПИСОК НА СТУДЕНТИ ЗА ВЕЖБИ ПО МЕДИЦИНСКИ ОСНОВИ НА ИНВАЛИДНОСТА 2017/2018

Почитувани студенти,

За една седмица почнуваат предавањата по предметот Медицински основи на инвалидноста, а за две седмици и вежбите. Во прилог ви го давам списокот по групи и тој е преземен од списоците по ХГ и ФФА на почетокот на академската година. Затоа, однапред знам дека има некои недостатоци. Ги замолувам сите студенти кои ги нема на списокот да се пријават најдоцна до четврток 08.02.2018 година до 14:00 часот за да можам да ги впишам во списокот за предавања, како и за вежби. Знам дека некои подоцна се запишуваа, некои се префрлуваа од редовни во вонредни студенти и обратно. Редовните студенти од повозрасните генерации кои никогаш не земале потпис по овој предмет задолжително да ми се пријават. Сите измени, замени да ги пријавите на мојата службена пошта. Ве информирам на време да си набавите литература во книжарницата на Литература.МК.

I група
Вторник
10.45-13.00 часот

1. 24527/17
2. 24206/17
3. 10080/17
4. 24509/17
5. 24516/17
6. 10062/17
7. 10114/17
8. 10009/17
9. 10039/17
10. 10024/17
11. 24515/17
12. 24529/17
13. 10109/17
14. 24539/17
15. 24590/17
16. 10084/17
17. 10070/17
18. 10055/17
19. 24577/17
20. 24510/17
21. 24572/17
22. 10097/17
23. 10075/17
24. 24535/17
25. 24569/17
26. 10042/17
27. 24549/17
28. 10027/17
29. 10113/17
30. 10096/17
31. 10074/17

II група
Четврток
09.00-11.15 часот

1. 24585/17
2. 24208/17
3. 24523/17
4. 10051/17
5. 24560/17
6. 24557/17
7. 10032/17
8. 24508/17
9. 24574/17
10. 24571/17
11. 10107/17
12. 24522/17
13. 24565/17
14. 10110/17
15. 24209/17
16. 24547/17
17. 24513/17
18. 10046/17
19. 10102/17
20. 10111/17
21. 10058/17
22. 24553/17
23. 10101/17
24. 10090/17
25. 24506/17
26. 10028/17
27. 10112/17
28. 24538/17
29. 10038/17
30. 24543/17
31. 10089/17 

Предметен наставник

Содржина на учебникот МОИ

Почитувани студенти,

Од денес учебникот по Медицински основи на инвалидноста ќе можете да го купите во книжарницата Литература.МК што се наоѓа на улица Македонија, спроти спомен куќата на Мајка Тереза во центарот на градот. Количините се ограничени и затоа побрзајте за да не чекате потоа на ново печатење. Напоменувам дека има доста бонус поглавја кои би можеле да ви полсужат за студирање на втор или трет циклус на студии. Книжарницата работи и во сабота. За да знаете што купувате, должен сум да ви ја споделам содржината на истиот:

1. НЕРВЕН СИСТЕМ

2. ПОИМ ЗА МЕНТАЛНА РЕТАРДАЦИЈА

3. ЕПИДЕМИОЛОГИЈА НА МЕНТАЛНАТА РЕТАРДАЦИЈА

4. ЕТИОЛОГИЈА НА МЕНТАЛНАТА РЕТАРДАЦИЈА 

5. ХРОМОЗОМОПАТИИ И МЕНТАЛНА РЕТАРДАЦИЈА

6. МЕТАБОЛНИ РАСТРОЈСТВА И МЕНТАЛНА РЕТАРДАЦИЈА

7. ПРЕГЛЕД НА МЕНТАЛНО РЕТАРДИРАНО ЛИЦЕ 

8. ТРЕТМАН И ПРОГНОЗА НА МЕНТАЛНАТА РЕТАРДАЦИЈА

9. ПРЕВЕНЦИЈА НА МЕНТАЛНАТА РЕТАРДАЦИЈА

10. ШИЗОФРЕНИЈА ВО ДЕТСКАТА ВОЗРАСТ

11. АУТИЗАМ

12. RETT-ОВ СИНДРОМ

13. ХИПЕРКИНЕТСКИ СИНДРОМ (АДХД)

14. ЕПИЛЕПСИЈА

15. АНАТОМИЈА И ФИЗИОЛОГИЈА НА МОТОРНИОТ СИСТЕМ

16. ЦЕРЕБРОВАСКУЛАРНИ БОЛЕСТИ

17. МИОПАТИИ

18. НЕВРОПАТИИ.

19. MYASTHENIA GRAVIS

20. МУЛТИПНА СКЛЕРОЗА

21. ЦЕРЕБРАЛНА ПАРАЛИЗА

22. РАЗВОЈНИ ЗАБОЛУВАЊА НА НЕРВНИОТ СИСТЕМ

23. ТРАУМАТСКИ ПОВРЕДИ НА ГЛАВА И ЦНС

24. НЕВРОКУТАНИ СИНДРОМИ

25. АНАТОМИЈА И ФИЗИОЛОГИЈА НА УВО

26. МЕТОДИ НА ИСПИТУВАЊЕ НА СЛУХОТ

27. АНАТОМИЈА И ФИЗИОЛОГИЈА НА РАМНОТЕЖА

28. КОНГЕНИТАЛНИ МАЛФОРМАЦИИ НА УВО

29. ВОСПАЛЕНИЈА НА УВО

30. МЕНИЕРОВА БОЛЕСТ (MORBUS MENIERE)

31. ТУМОРИ НА УВО

32. ОТОСКЛЕРОЗА

33. НАГЛУВОСТ И ГЛУВОСТ

34. АНАТОМИЈА И ФИЗИОЛОГИЈА НА ЛАРИНКС

35. ФИЗИОЛОГИЈА НА ГОВОР

36. ОСНОВИ НА ФОНИЈАТРИЈА

37. АНАТОМИЈА НА ОКО

38. ОФТАЛМОЛОШКИ ТЕСТОВИ

39. РЕФРАКЦИЈА И АКОМОДАЦИЈА НА ОКО

40. МОТОРИКА НА ОКО

41. ПАТОЛОШКИ ПРОМЕНИ НА ЛЕЌА

42. ПОВРЕДИ НА ОКО

43. ВОСПАЛЕНИЈА НА ОКО

44. ГЛАУКОМ

45. ЗАБОЛУВАЊА НА ОЧНИОТ НЕРВ

46. ЗАБОЛУВАЊА НА РЕТИНА

47. ФУНКЦИОНАЛНА АМБЛИОПИЈА

48. ЛИТЕРАТУРА

ПРИЛОГ 1 МЕДИЦИНСКИ РЕЧНИК

ИНДЕКС НА ЗБОРОВИ

БЕЛЕШКА ЗА АВТОРОТ

Предметен наставник

Литература по предметот МОИ

Почитувани студенти од прва година,

На 13.02.2018 година почнуваме со предавањата па решив да ви ја постирам потребната литература по предметот Медицински основи на инвалидноста. Во прилог е фотографијата од корицата на мојот учебник. Учебникот ќе може да се набави во книжарницата на Литература.МК на улица Македонија во центарот на главниот град по цена од 1000 денари која 10 години стои исто, иако постои инфлација во општеството и се воведуваат разни даноци од страна на државата.

 Литература:

1. Трајковски В. Медицински основи на инвалидноста. Филозофски факултет, Институт за дефектологија, Скопје, 2008.
2. Трајковски В. Фонијатрија (скрипта за внатрешна употреба). Филозофски факултет, Институт за дефектологија, Скопје, 2009.
3. Lević Z. Osnovi savremene neurologije. Zavod za udžbenike i nastavna sredstva, Beograd, 2000.
4. Radulović R, Stanković P. Otorinolaringologija sa maksilofacijalnom hirurgijom. Medicinski fakultet, Beograd, 2004.
5. Бредфорд СА. Основи на офталмологијата. Табернакул, Скопје, 2010.

Предметен наставник