Цитиран наш труд објавен во Focus Autism Other Devеlopmental Disablities

Почитувани колешки и колеги,
Уште еднаш цитиран нашиот труд: Trajkovski V, Petlichkovski A, Efinska-Mladenovska O, et al. Higher plasma concentration of food-specific antibodies in persons with autistic disorder in comparison to their siblings. Focus Autism Other Dev Disabl.2008;23:176–185 и тоа во трудот The Relationship of Autism and Gluten од Timothy Buie, Harvard Medical School, Massachusetts General Hospital for Children, Boston, Massachusetts во списанието Clinical Therapeutics/Volume 35, Number 5, 2013 под референца 30. Нека ни се множат цитирањата. Во продолжение само апстрактот бидејќи трудот не е со слободен пристап.
Авторот

ABSTRACT
Background: Autism is now a common condition with a prevalence of 1 in 88 children. There is no
known etiology. Speculation about possible treatments for autism or autism spectrum disorders
(ASD) has included the use of various dietary interventions, including a gluten-free diet.
Objective: The goal of this article was to review the literature available evaluating the use of glutenfree
diets in patients with autism to determine if diet should be instituted as a treatment.
Methods: A literature review was performed, identifying previously published studies in which a
gluten-free diet was instituted as an autism treatment. These studies were not limited to randomized
controlled trials because only 1 article was available that used a double-blind crossover design. Most
publish reports were unblinded, observational studies.
Results: In the only double-blind, crossover study, no benefit of a gluten-free diet was identified. Several
other studies did report benefit from gluten-free diet. Controlling for observer bias and what may have
represented unrelated progress over time in these studies is not possible. There are many barriers to
evaluating treatment benefits for patients with autism. Gluten sensitivity may present in a variety of
ways, including gastrointestinal and neurologic symptoms. Although making a diagnosis of celiac
disease is easier with new serology and genetic testing, a large number of gluten-sensitive patients do
not have celiac disease. Testing to confirm non–celiac gluten sensitivity is not available.
Conclusions: A variety of symptoms may be present with gluten sensitivity. Currently, there is insufficient
evidence to support instituting a gluten-free diet as a treatment for autism. There may be a subgroup
of patients who might benefit from a glutenfree diet, but the symptom or testing profile of these
candidates remains unclear.
Key words: autism, autism spectrum disorders, diet, gluten, treatment.